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Supplementary Information 2: Assay Methods & Results

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Figshare2025-11-22 更新2026-04-08 收录
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https://figshare.com/articles/dataset/Supplementary_Information_2_Assay_Methods_Results/27110170/2
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The paper displays an exemplification of antiorganotrophism (tissue reduction) in vivo utilising ovine materials obtained from adult ewes. Ovine plasma was subjected to a bioassay-guided fractionation utilising a rat organometric assay that was conducted according to a standardised method over four days with intraperitoneal dosing. Organ shrinkage was readily provoked in what is a relatively crude assay in vivo. In cell culture experiments, shrinkage of rat bone marrow stem cells could be readily demonstrated using neat plasma from ovary-intact sheep, with such activity lacking in plasma from ovariectomised sheep
提供机构:
Davies, Keith G; r mundy, Christopher; Newton, Russell P.; c hart, aurelia; Hart, John E; Howlett, David
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2024-12-05
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