Simple clinical indices assessed in the studies and their association with survival to discharge.

All numbers represent median (interquartile range) except where stated.aHeart rate was not recorded in SEAQUAMAT;bOxygen saturation was only measured in the two smaller studies;cOligo-anuria was not recorded in the Bangladeshi study. MAP: Mean arterial pressure; mmHg: millimetres of mercury; GCS: Glasgow Coma Score; RCAM: Respiratory Coma Acidosis Malaria score;