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Gold(I)-Catalyzed Macrocyclization of 1,<i>n</i>‑Enynes

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NIAID Data Ecosystem2026-03-07 收录
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The gold(I)-catalyzed [2 + 2] cycloaddition of large 1,n-enynes (n = 10–16) provides access to 9- to 15-membered ring macrocycles incorporating a cyclobutene moiety. The reaction requires the use of a gold(I) catalyst bearing a sterically hindered biphenylphosphine ligand.

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2013-04-05
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