Proteomic Investigation Reveals Dominant Alterations of Neutrophil Degranulation and mRNA Translation Pathways in COVID-19 Patients. Bankar et. al.

This dataset comprises of supplementary files for the comprehensive proteomics-based investigation of nasopharyngeal swab samples from COVID-19 patients. The table S1 shows the clinical characteristics of COVID-19 patients, Related to Figure 1. The table S8 shows the refined list of transitions prepared using skyline software for MRM assay of clinical marker proteins, Related to Figure 3. The table S10 is related to the in-silico docking, showing the list of FDA approved drug and details of drug binding to the target proteins detected using mass-spectrometry analysis, Related to Figure 5.

本数据集包含针对新冠（COVID-19）患者鼻咽拭子样本开展的全面蛋白质组学研究的补充文件。表S1展示了新冠患者的临床特征，与图1相关。表S8列出了使用Skyline软件为临床标志物蛋白的多反应监测（MRM）分析所优化的离子跃迁列表，与图3相关。表S10与计算机模拟分子对接（in silico docking）相关，包含经美国食品药品监督管理局（FDA）批准的药物列表，以及经质谱（mass spectrometry）分析检测到的靶标蛋白与药物的结合详情，与图5相关。