Human Microglia Engraftment in Mice
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This study investigates species-specific differences in CSF1R signaling to enable robust engraftment of human pluripotent stem cell-derived microglia (hMGs) into immunodeficient mouse brains without genetic modification. Flow cytometry was used to quantify hMG survival, engraftment efficiency, and maturation markers following PLX5622 treatment and transplantation.
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ImmPort创建时间:
2026-03-26



