David Ball, Jean Peccoud (2011) CIL:35747, Saccharomyces cerevisiae. CIL. Dataset

A time lapse experiment of Saccharomyces cerevisiae expressing GFP-tagged SIC1.

SIC1 is an inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1

These phase, gfp images are part of an image group that ranges from CIL:35740-35759. Note that there are additional groups showing time series of other cell cycle regulation proteins by the same authors in the Library.

一项关于表达GFP标记的SIC1蛋白的酿酒酵母（Saccharomyces cerevisiae）的延时摄影实验。SIC1蛋白作为一种Cdc28-Clb激酶复合物的抑制剂，调控G1/S期转换，防止S期的提前启动，确保基因组完整性；其磷酸化作用将Sic1p蛋白靶向SCF(CDC4)依赖性降解；是哺乳动物Kip1蛋白的功能同源物。这些调控阶段的GFP图像组成为CIL:35740-35759图像库中的一部分。请注意，该库中还包括由同一作者提供的其他细胞周期调控蛋白的时间序列图像组。