Table S1 - Class IA PI3Kinase Regulatory Subunit, p85α, Mediates Mast Cell Development through Regulation of Growth and Survival Related Genes
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List of genes altered in p85α−/− MCp's in response to SCF stimulation. Low density mononuclear cells (LDMNC) were isolated from three pairs of WT and p85α−/− mice and cultured independently in the presence of IL-3 (10 ng/mL) for 1 week. KIT and IgE receptor double positive mast cells were sorted by using FACS. Sorted mast cells were stimulated with SCF (100 ng/mL) for 48 hours and then sent for microarray analysis for gene expression profiling. Altered expression of genes in p85α−/− MCp's in response to SCF stimulation compared to WT controls were listed in Table S1. (DOC)
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2015-12-02



