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IL-27 stimulation in Foxp3+ Tregs improves suppressive function and therapeutic efficacy

ChEBI2015-11-01 更新2026-07-12 收录

调节性T细胞功能

免疫治疗优化

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-63455 数据链接链接失效反馈

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IL-27 stimulation in Foxp3+ Tregs improves suppressive function and therapeutic efficacy

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创建时间：

2015-11-01

调节性T细胞功能

免疫细胞转录组学

LKB1 deficiency in Treg cells impairs their survival, metabolism and suppressive function. To exclude the impact of excessive inflammation on LKB1-deficient Treg cells, we generated mixed bone marrow

NIAID Data Ecosystem50

Functional Analysis and Gene Expression Profile of Umbilical Cord Blood Regulatory T Cells. Homo sapiens

调节性T细胞功能

脐带血免疫调节

Since the role of cord blood (CB) regulatory T cells (Tregs) for the suppression of the allogeneic T-cell response is under investigation, we analyzed and compared the functional properties and gene e

NIAID Data Ecosystem10

Supplementary Table 1 from Reshaping the Tumor Microenvironment of KRAS G12D Pancreatic Ductal Adenocarcinoma with Combined SOS1 and MEK Inhibition for Improved Immunotherapy Response

胰腺癌治疗

免疫治疗优化

Supplementary Table 1

NIAID Data Ecosystem00

Human Regulatory T Cell Suppressive Function Is Independent of Apoptosis Induction in Activated Effector T Cells

调节性T细胞功能

自身免疫疾病机制

BackgroundCD4+CD25+FOXP3+ Regulatory T cells (Treg) play a central role in the immune balance to prevent autoimmune disease. One outstanding question is how Tregs suppress effector immune responses in

NIAID Data Ecosystem40

Learning the sequence code for mRNA and protein abundance in human immune cells

基因表达调控

免疫治疗优化

mRNA and protein abundance are defined by transcriptional and post-transcriptional regulatory mechanisms. Here, we develop a machine learning pipeline, termed SONAR, to decipher the endogenous sequenc

NIAID Data Ecosystem00

IL-27 stimulation in Foxp3+ Tregs improves suppressive function and therapeutic efficacy

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