2022 RedishLab: medial prefrontal subregions recorded from rats on restaurant row

We recorded from the full dorso-ventral extent of mPFC in each of 8 rats, as they performed a complex economic decision task. These data revealed four distinct functional domains within mPFC that closely mirrored anatomically-identified subregions, including novel evidence to divide prelimbic cortex into dorsal and ventral components. We found that dorsal aspects of mPFC (ACC, dPL) processed information about active decisions, while ventral aspects (vPL, IL) were more engaged in motivational factors.

Methods: Neural ensembles recorded from silicon probes in the medial prefrontal regions of 8 rats running the Restaurant Row task with both offer and wait zones. For full methods see Diehl, G. W., & Redish, A. D. (2022). Differential processing of decision information in subregions of rodent medial prefrontal cortex.
Usage Notes

MATLAB code to open data files is included with the data archive. (Originally analyzed with MATLAB 2017b.)

我们对8只大鼠的背腹全长的内侧前额叶皮层（mPFC）进行了记录，在它们执行复杂的经济决策任务时。这些数据揭示了mPFC内存在四个不同的功能区域，这些区域与解剖学上识别的亚区紧密对应，包括将初级前皮层分为背侧和腹侧成分的新证据。我们发现，mPFC的背侧部分（ACC、dPL）处理有关主动决策的信息，而腹侧部分（vPL、IL）则更多参与动机因素的处理。

方法：通过硅制探针记录了8只执行餐厅行任务（含提供和等待区域）的大鼠内侧前额叶区域神经集合。有关详细方法，请参阅Diehl, G. W. & Redish, A. D. (2022)发表的《啮齿类内侧前额叶皮层亚区的决策信息处理差异》。

使用说明：数据档案中包含打开数据文件的MATLAB代码。（最初使用MATLAB 2017b进行分析。）