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Delineating Noncovalent Interactions between the Azinomycins and Double-Stranded DNA: Importance of the Naphthalene Substitution Pattern on Interstrand Cross-Linking Efficiency

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NIAID Data Ecosystem2026-03-06 收录
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Using a series of synthetic azinomycin analogues, it is shown that the efficiency of in vitro DNA interstrand cross-linking is markedly reduced when either the C-5‘ methyl group or both the C-5‘ methyl and C-3‘ methoxy groups are deleted from the naphthalene ring.

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2004-09-30
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