The model defines three different tumor cell types: un-intoxicated, intoxicated, and dead cells, with densities ρ1, ρ2, and ρ3, respectively. The un-intoxicated cells proliferate, but the intoxicated
This study generated ErbB2-specific CAR-T and CAR-CIK (cytokine induced killer) cells from peripheral blood mononuclear cells by lentiviral transduction. Transduced and untransduced parental cells wer
RATIONALE: The LMB-9 immunotoxin may be able to locate tumor cells and kill them without harming normal cells. This may be an effective treatment for advanced solid tumors. PURPOSE: Phase I trial to s