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Synthesis of the ABC Tricyclic System of Daphnicyclidin A

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NIAID Data Ecosystem2026-03-10 收录
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A substrate-stereocontrolled synthesis of the ABC tricyclic system of daphnicyclidin A is developed. The key reactions include an efficient tandem N-allylation–SN2′ reaction to assemble 2,3,4-cis trisubstituent pyrrolidine ring C and two intramolecular Horner–Wadsworth–Emmons reactions to construct cycloheptanone ring A and piperidine ring B.

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2017-03-15
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