Solvent-Switched Manganese(I)-Catalyzed Regiodivergent Distal vs Proximal C–H Alkylation of Imidazopyridine with Maleimide
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https://figshare.com/articles/dataset/Solvent-Switched_Manganese_I_-Catalyzed_Regiodivergent_Distal_vs_Proximal_C_H_Alkylation_of_Imidazopyridine_with_Maleimide/16645951
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资源简介:
A sustainable Mn(I)-catalyzed exclusive
solvent-dependent functionalization
of imidazopyridine with maleimide via an electrophilic metalation
at the distal (in 2,2,2-trifluoroethanol (TFE)) and chelation assisted
at the proximal (in tetrahydrofuran (THF)) has been developed. The
strategy was successfully applied to the drug Zolimidine and a broad
range of substrates, thereby reflecting the method’s versatility.
创建时间:
2021-09-20



