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Dynamic regulation of the COP9 signalosome: Insights into the spatial localization and subunit versatility of the complex

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NIAID Data Ecosystem2026-03-11 收录
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https://www.omicsdi.org/dataset/pride/PXD000277
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HeLa cells were fracitonated into nuclear soluble, chromatin bound and cytosolic. Extracts were immunoprecipitated with a CSN3 antibody, then eluted with glycine. Proteins were digested, then enriched for phosphopeptides. Samples were analyzed on an LTQ-Orbitrap. Data was analyzed using the TRansOMics software for time alignment and feature detection. MS/MS spectra searched using Mascot.
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2019-11-25
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