Cobalamin related parameters.

Medians (interquartile ranges) [reference ranges] are shown for Cbl related parameters in patients referred for measurement of serum Cbl divided according to Cbl supplementation (n = 818).aOnly non-supplemented patients with normal kidney function (eGFR ≥60 mL/min/1.73 m2, n = 503).bNumbers and percentages of non-supplemented patients with normal kidney function and serum Cbl >250 pmol/L [31] showing biochemical Cbl deficiency, defined as holoTC 0.28 µmol/L. P-values were obtained by comparing medians across Cbl groups using Kruskal-Wallis test. Abbreviations: Cbl: cobalamin, vitamin B12; holo transcobalamin: Cbl-saturated transcobalamin; sCD320: soluble transcobalamin receptor CD320; MMA: methylmalonic acid; eGFR: estimated glomerular filtration rate.