Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells

NIAID Data Ecosystem2026-03-11 收录

胚胎表观遗传调控

PRC2复合体

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE42155 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2019-05-15

Additional file 2: of Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner

产前砷暴露效应

胚胎表观遗传调控

Associations of candidate gene expression in fetal placenta with maternal U-As. Multivariable linear regression analysis was performed to determine the association between log-transformed maternal U-A

NIAID Data Ecosystem100

H2A.Z Facilitates Access of Active and Repressive Complexes to Chromatin in Embryonic Stem Cell Self-renewal and Differentiation

胚胎表观遗传调控

组蛋白变体H2A

Chromatin modifications have been implicated in the self-renewal and differentiation of embryonic stem cells (ESCs). However, the function of histone variant H2A.Z in ESCs remains unclear. We show tha

NIAID Data Ecosystem40

GC-rich Sequence Elements Recruit Polycomb Repressive Complex 2 (PRC2) in ES cells. Mus musculus

PRC2复合体

CpG岛

Polycomb proteins are epigenetic regulators that localize to developmental loci in the early embryo where they mediate lineage-specific gene repression. In Drosophila, these repressors are recruited t

NIAID Data Ecosystem20

Identification of JARID2/PRC2 interactome in human embryonic stem cells

PRC2相互作用组

胚胎表观遗传调控

JARID2 is an integral subunit of the chromatin modifier PRC2 (Polycomb Repressive Complex 2). PRC2 methylates lysine 27 in histone H3 and is required for human development. Mutaitons of PRC2 subunits

NIAID Data Ecosystem50

PRC1 and PRC2 proximal interactome in mouse embryonic stem cells [ChIP-Seq]. PRC1 and PRC2 proximal interactome in mouse embryonic stem cells [ChIP-Seq]

多梳复合物相互作用组

胚胎表观遗传调控

Polycomb Repressive Complexes PRC1 and PRC2 play a crucial role in silencing lineage-specific genes during early embryogenesis. To provide new insights in polycomb biology, we profiled the proximal in

NIAID Data Ecosystem30

Hira-dependent histone H3.3 deposition facilitates PRC2 recruitment at developmental loci in ES cells

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