Facile 5-Endo Amidyl Radical Cyclization Promoted by Vinylic Iodine Substitution
收藏NIAID Data Ecosystem2026-03-06 收录
下载链接：
https://figshare.com/articles/dataset/Facile_5_Endo_Amidyl_Radical_Cyclization_Promoted_by_Vinylic_Iodine_Substitution/3374890
下载链接
链接失效反馈官方服务：
资源简介：
BF3·OEt2-catalyzed atom-transfer radical addition of iodoacetamides to alkynes yielded the corresponding vinyl iodides, which upon treatment
with tBuOCl and I2 afforded γ-lactam derivatives in moderate to good yield. The mechanism was proposed to be 5-endo amidyl radical cyclization,
and vinylic iodine substitution provided the driving force for the cyclization.
创建时间：
2016-05-12
