ITC derived thermodynamic parameters for the binding of polyamines to MLDNAa.
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aAll the data in this table are derived from ITC experiments conducted in 20 mM [Na+] citrate-phosphate buffer, pH 7.0 and are average of four determinations, Ka and ΔHo values were determined from ITC profiles fitting to Origin 7 software as described in the text. The values of ΔGo and TΔSo were determined using the equation ΔGo = −RTlnKa, and TΔSo = ΔHo−ΔGo. All the ITC were fit to a model of single binding sites.
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2015-12-02



