GVTGIAQ segment 147-153 from Human Superoxide Dismutase with I149T mutation associated with a familial form of amyotrophic lateral sclerosis

Protein Data Bank Japan2024-02-28 更新2026-03-21 收录

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GVTGIAQ segment 147-153 from Human Superoxide Dismutase with I149T mutation associated with a familial form of amyotrophic lateral sclerosis Descriptor: GVTGIAQ segment from Superoxide dismutase [Cu-Zn] Authors: Sievers, S.A, Sawaya, M.R, Eisenberg, D, Ivanova, M.I. Deposit date: 2013-11-06 Release date: 2013-12-04 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Aggregation-triggering segments of SOD1 fibril formation support a common pathway for familial and sporadic ALS. Proc.Natl.Acad.Sci.USA, 111, 2014

本数据集对应携带与家族性肌萎缩侧索硬化（amyotrophic lateral sclerosis, ALS）相关I149T突变的人源超氧化物歧化酶（Superoxide Dismutase, SOD1）的147~153位GVTGIAQ肽段。描述：来自铜锌超氧化物歧化酶的GVTGIAQ肽段作者：Sievers, S.A、Sawaya, M.R、Eisenberg, D、Ivanova, M.I. 提交日期：2013-11-06 发布日期：2013-12-04 最后更新：2024-02-28 检测方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.3 Å）引用文献：《SOD1纤维形成的聚集触发片段为家族性与散发性肌萎缩侧索硬化共享通路提供佐证》，Proc. Natl. Acad. Sci. USA，第111卷，2014年

创建时间：

2013-11-06