Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water

Structural analysis of substrate-mimicking inhibitors in complex with Neisseria meningitidis 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase - the importance of accommodating the active site water Descriptor: L-PHOSPHOLACTATE, MANGANESE (II) ION, PHOSPHATE ION, ... Authors: Heyes, L.C, Reichau, S, Cross, P.J, Parker, E.J. Deposit date: 2014-05-16 Release date: 2014-10-08 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water. Bioorg.Chem., 57, 2014

脑膜炎奈瑟菌（Neisseria meningitidis）3-脱氧-D-阿拉伯庚酮糖-7-磷酸合酶（3-deoxy-D-arabino-heptulosonate 7-phosphate synthase）复合物中底物模拟抑制剂（substrate-mimicking inhibitors）的结构分析——适配活性位点水（active site water）的重要性
配体描述符：L-磷酸乳酸、锰(II)离子、磷酸根离子……
作者：Heyes, L.C、Reichau, S、Cross, P.J、Parker, E.J.
提交日期：2014-05-16
发布日期：2014-10-08
最后更新日期：2024-01-10
实验方法：X射线衍射（X-ray diffraction，分辨率2.34 Å）
引用文献：Structural Analysis of Substrate-Mimicking Inhibitors in Complex with Neisseria Meningitidis 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase - the Importance of Accommodating the Active Site Water. Bioorg.Chem., 57, 2014