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Mechanism of lethal toxin neutralization by a human monoclonal antibody specific for the PA(20) region of Bacillus anthracis protective antigen.

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To identify the PA residues required for mAb binding, a yeast library displaying randomly mutated PA on its surface was screened using flow cytometry and those yeast clones that had lost the ability to bind were sequenced.

提供机构:
IEDB
创建时间:
2011-01-01
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