A phenotypic rescue approach identifies lineage regionalization defects in a mouse model of DiGeorge syndrome.
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https://www.ncbi.nlm.nih.gov/sra/SRP383159
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Evaluate the effect of the vB12 treatment on transcriptional profile of Tbx1 haploinsufficiency embryos we performed RNA-seq on whole E9.5 mouse embryos (21 somite stage) after treatment with vB12 (cyanocobalamin Sigma-Aldrich Prod. Number V2876) or vehicle (PBS) during pregnancy Overall design: Comparative gene expression profiling analysis of RNA-seq data from PBS-treated WT (n=3), PBS-treated Tbx1+/- (n=3), and vB12-treated Tbx1+/- (n=2) embryos
创建时间:
2022-10-29



