Risk factors for invasive Group B Streptococcal (GBS) disease in early-onset and late-onset disease cases and matched controls.

1Univariate-OR(95%CI)-calculated odds ratio with 95% confidence using Fischer exact test comparing cases and controls.2 Multivariate-OR(95%CI)-calculated odds ratio with 95% confidence of disease using conditional logistic regression (For early-onset disease: adjusted for HIV-status, maternal age at delivery, gestational age, maternal GBS colonization, prolonged ROM, offensive liquor, maternal temperature>38, GBS bacteriuria and any intra-partum antibiotics. For late-onset disease: adjusted for HIV-status, maternal age at delivery, gestational age, maternal GBS colonization and GBS bacteriuria).3 Prolonged ROM (>18 hours)-prolonged rupture of membranes.4Maternal fever during labor.5IAP-Intrapartum antibiotic prophylaxis to pregnant women that met risk-based criteria (gestation Risk factors for invasive Group B Streptococcal (GBS) disease in early-onset and late-onset disease cases and matched controls.