Human Pol Kappa holoenzyme with Ub-PCNA Descriptor: DNA Primer, DNA Template, DNA polymerase kappa, ... Authors: Lancey, C, De Biasio, A, Hamdan, S.M. Deposit date: 2021-03-15 Release date: 2021-11-03
Maintaining genome integrity presents a particular challenge for plants due to their sedentary lifestyle, which disables direct avoidance of unfavorable external conditions. Additionally, plants’ meta
Double-strand breaks (DSBs) are critical lesions in genomic DNA, and their accurate repair is essential for maintaining genome stability. The nuclear actin cytoskeleton has been implicated in homology
Cohesin and the PBAF chromatin remodelling complex are required to repress transcription at sites of DNA double strand breaks. To investigate this and rule out known sister-chromatid dependent functio
Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that