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ROS-Specific Huntingtin Interactions: Mass spec analysis of ROS-treated mouse striatal cells

Name: ROS-Specific Huntingtin Interactions: Mass spec analysis of ROS-treated mouse striatal cells
Creator: McMaster University
Published: 2018-01-29T00:00:00+08:00

Zenodo2018-01-29 更新2026-04-07 收录

ROS特异性亨廷顿蛋白相互作用

亨廷顿病分子机制

数据链接：

https://zenodo.org/record/1162264 数据链接链接失效反馈

官方服务：

资源简介：

Mass spec identification of ROS-specific huntingtin protein-protein interactions.

应用场景：

提供机构：

McMaster University

创建时间：

2018-01-29

神经细胞分化

亨廷顿病分子机制

Mutation in the huntingtin (HTT) gene causes Huntingtonâs disease. Wild type Htt is essential for development as Htt knockout mice die at day E7.5. Increasing evidence suggests mutant Htt may alter

NIAID Data Ecosystem80

Gene expression profiling of FACS-purified striatal medium spiny neurons in Huntington's disease model mouse. Gene expression profiling of FACS-purified striatal medium spiny neurons in Huntington's disease model mouse

亨廷顿病分子机制

神经元基因表达

Gene expression profiling of purified medium spiny neurons (MSNs) in R6/2 Huntington’s disease (HD) model mouse. To purify MSNs by FACS, R6/2 was crossed with Scn4b-Venus transgenic mouse expressing V

NIAID Data Ecosystem70

Targeting H3K4 methylation as a therapeutic strategy for Huntington's disease (RNA-seq). Mus musculus

亨廷顿病分子机制

表观遗传调控

Transcriptional dysregulation is an early feature of Huntington's disease (HD). We observed gene-specific changes in H3K4me3 at transcriptionally repressed promoters in R6/2 mouse and human HD brain.

NIAID Data Ecosystem30

ER_RNASeq_LAQ5MGvsCONTROL.xlsx

亨廷顿病分子机制

RNA测序分析

The RNASeq Raw data related to the article of "Phosphorylation of myelin regulatory factor by PRKG2 mediates demyelination in Huntington's disease" Figure 4

NIAID Data Ecosystem70

Expression data from 9 and 13 weeks old TIFIAD1Cre mice

亨廷顿病分子机制

神经元基因表达

We have investigated the p53-dependent stress response in medium spiny neurons (MSNs) that degenerate in Huntington’s disease. To induce p53 signaling cascade, we have genetically inactivated by the C

NIAID Data Ecosystem40

ROS-Specific Huntingtin Interactions: Mass spec analysis of ROS-treated mouse striatal cells

资源简介：

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