Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt3 at top of spiral staircase (locally refined on the AAA+ motor)
收藏Protein Data Bank Japan2025-12-24 更新2026-04-25 收录
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Nub1/Fat10-processing human 26S proteasome bound to Txnl1 with Rpt3 at top of spiral staircase (locally refined on the AAA+ motor) Descriptor: 26S protease regulatory subunit 10B, 26S protease regulatory subunit 8, 26S proteasome non-ATPase regulatory subunit 14, ... Authors: Arkinson, C, Gee, C.L, Martin, A. Deposit date: 2024-11-05 Release date: 2024-12-04 Last modified: 2025-12-24 Method: ELECTRON MICROSCOPY (3.62 Å) Cite: Structural landscape of the degrading 26S proteasome reveals conformation-specific binding of TXNL1. Nat.Struct.Mol.Biol., 32, 2025
该数据集对应经Nub1/Fat10加工的人类26S蛋白酶体(26S proteasome),其与Txnl1结合,螺旋梯顶部带有Rpt3,且在AAA+马达(AAA+ motor)区域完成局部精修。描述项包含:26S蛋白酶体调节亚基10B(26S protease regulatory subunit 10B)、26S蛋白酶体调节亚基8(26S protease regulatory subunit 8)、26S蛋白酶体非ATP酶调节亚基14(26S proteasome non-ATPase regulatory subunit 14)等。作者:阿特金森(Arkinson)C、吉(Gee)C.L.、马丁(Martin)A.。提交日期:2024年11月5日;发布日期:2024年12月4日;最后修改日期:2025年12月24日。实验方法:电子显微镜(分辨率3.62埃)。引用文献:《降解状态26S蛋白酶体的结构全景揭示TXNL1的构象特异性结合》(英文原标题:Structural landscape of the degrading 26S proteasome reveals conformation-specific binding of TXNL1),发表于《自然·结构与分子生物学》(Nat.Struct.Mol.Biol.)2025年,第32卷。
创建时间:
2024-11-05



