To test the impact of TRAP-6 on T-cell activation, we used CD3/CD28 dynabeads-stimulated mouse T cells and treated the cells with vehicle control or 0.01 mmol/L TRAP-6 for 24 h. RNA was extracted from
Vγ9Vδ2 T cells play an important role in the development and progression of psoriasis vulgaris (PV), but how they promote skin inflammation and the molecular mechanisms underlying Vγ9Vδ2 T cell dysfun
Allergen-specific immunotherapy has major effects on the frequency of peripheral Tfh and Tfr cells, which may be regulated by IL-2 RNA-sequencing of sorted memory CXCR5 high and CXCR5low T cells from
Comparison of transcriptome between control and Tcf1/Lef1-deficient Treg cells Splenocytes were harvested from Foxp3-Cre+, Tcf1/Lef1 wild-type or double floxed mice (male and at 16 weeks of age), and
BackgroundIntestinal transplantation (ITx) represents the only curative option for patients with irreversible intestinal failure. Nevertheless, its rejection rate surpasses that of other solid organ t
