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The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila

ChEBI2008-11-18 更新2026-07-21 收录

果蝇剂量补偿

染色质靶向机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-11817 数据链接链接失效反馈

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The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila

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创建时间：

2008-11-18

果蝇剂量补偿

II型拓扑异构酶

Investigate Topo II levels in dosage compensated and non-dosage compensated genes Dosage compensation refers to the equalization of most X-linked gene products between males and females. In Drosophila

NIAID Data Ecosystem80

The maleless gene mitigates global aneuploid effect and evolutionary shift from X to autosomes. Drosophila melanogaster

果蝇剂量补偿

非整倍体效应进化

During sexual dimorphism, the loss of one entire X chromosome in Drosophila males is achieved largely via a broad genome-wide aneuploid effect. Exploring how MSL proteins and two large non coding RNAs

NIAID Data Ecosystem40

Autoregulation of the Drosophila Noncoding roX1 RNA Gene

非编码RNA调控

果蝇剂量补偿

Most genes along the male single X chromosome in Drosophila are hypertranscribed about two-fold relative to each of the two female X chromosomes. This is accomplished by the MSL (male-specific lethal)

Figshare2016-01-18 更新30

Mapping of MLE and MSL2 using iCLIP. Mapping of MLE and MSL2 using iCLIP

RNA结合蛋白

果蝇剂量补偿

Dosage compensation in Drosophila is an epigenetic phenomenon utilizing proteins and long non-coding RNAs (lncRNAs) for transcriptional up-regulation of the entire X-chromosome. Here, UV cross-linking

NIAID Data Ecosystem50

Targeting of the dosage-compensated male X-chromosome during early Drosophila development. Targeting of the dosage-compensated male X-chromosome during early Drosophila development

果蝇剂量补偿

早期胚胎发育

The essential process of dosage compensation, which corrects for the imbalance in X-linked gene expression between XX females and XY males, represents a key model for how genes are targeted for coordi

NIAID Data Ecosystem40

The MSL3 chromodomain directs a key targeting step for dosage compensation of the Drosophila

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