Expression of IL-4 regulated genes in GC-B cell LCL.

*Numbers in parentheses indicate the number of genes within the gene-set analyzed.Of the 21014 annotated genes in the U133 plus2 Affymetrix array platform, 484 were identified experimentally by Elo et al[35] as being down-regulated and 640 up-regulated by IL-4 in T cells. Gene-sets up- or down-regulated in EBV-transformed LCL from GC-B cells relative to uninfected GC-B cells were identified by Leonard et al[37]. For the determination of OR and statistical significance, equal sized probe-sets were compared by ranking probe-sets according to the magnitude of FC of the GCB-LCL relative to uninfected GC-B cells, and selecting the top 484 or 640 unique genes. Complete gene-lists are available in Data-File S2.