Ternary structure of Dpo4 bound to N7mG in the template base paired with incoming dCTP

NIAID Data Ecosystem2026-05-01 收录

DNA损伤修复

结构生物学

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Ternary structure of Dpo4 bound to N7mG in the template base paired with incoming dCTP

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2023-10-18

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

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LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE

结构生物学

核黄素生物合成

LUMAZINE SYNTHASE FROM SACCHAROMYCES CEREVISIAE Descriptor: 5-(6-D-RIBITYLAMINO-2,4-DIHYDROXYPYRIMIDIN-5-YL)-1-PENTYL-PHOSPHONIC ACID, LUMAZINE SYNTHASE Authors: Meining, W, Mortl, S, Fischer, M, Cush

Protein Data Bank Japan2024-02-07 更新10

FInnish National Protein Crystallography Consortium

蛋白质晶体学

结构生物学

The Finnish BAG encompasses 24 groups active in crystallography in Finland. The projects vary widely and include membrane proteins and protein complexes, other proteins involved...

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Measuring the structural impact of mutations on cytochrome P450 21A2, the major steroid 21-hydroxylase related to congenital adrenal hyperplasia

分子生物学

结构生物学

Congenital adrenal hyperplasia is an inherited autosomal recessive disorder related to deficient cortisol synthesis. The deficiency of steroid 21-hydroxylase (cytochrome P450 21A2), an enzyme involved

DataCite Commons2020-08-27 更新40

Structural studies of proteins and protein complexes involved in regulation, ...

蛋白质结构解析

结构生物学

Our BAG is focussed around a large group of experimenters who work on a diverse range of biological and physical problems. Whilst this makes it difficult to write an overall...

B2FIND10

Ternary structure of Dpo4 bound to N7mG in the template base paired with incoming dCTP

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