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Mucosal viral infection induces a regulatory T cell activation phenotype distinct from tissue residency in mouse and human tissues [single-cell RNA-seq]

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NIAID Data Ecosystem2026-03-13 收录
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Vaginal tissue Tregs acquire a inflammatory cytokine-dependent, infection-specific phenotype after local infection with HSV-2 Overall design: CD4+ FoxP3+ Tregs were isolated from the draining lymph nodes and vaginal tissue of FoxP3GFP mice +/- HSV-2 infection. These cells were then processed for transcriptional profiling using 5' whole transcriptomic approaches (10x)

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2022-04-15
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