The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic f
ENCODES a protein that exhibits PDZ domain binding; structural constituent of postsynaptic density; transmembrane transporter binding (ortholog); INVOLVED IN protein homooligomerization; excitatory po
ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN cytoskeleton organization (ortholog); lamellipodium assembly (ortholog); modification of postsynaptic actin cytoskeleton (ortholog
This allele is a spontaneously missense mutant found in a polycystic kidney diseased male Sprague Dawley rat. The mutation was a C to T transition that replaces an arginine by a tryptophan at amino ac
