Cell Reports; Nychyk et al 2021; Figure 1: Protein quality and quantity influence the effect of dietary fat on weight gain and tissue partitioning via host-microbiota changes

This experiment was done to analyze the impact of dietary macronutrients on body weight and energy intake. In total we used 18 different diets and tested these on males of one mouse strain (C57BL/6). This file contains the individual data and data per cage of male C57BL/6 mice exposed to 12 weeks feeding on one of 18 different diets. Body weight (BW) and energy intake (EI) recorded on weekly basis for each mouse (for BW) and per cage (for EI); final body weight gain calculated at the end of the study. Eleven to twelve animals were exposed to each diet. Dietary treatments consisted of three different levels of dietary fat (20, 40 and 55% by energy) combined with three different levels of protein (10, 20 and 30% by energy) with either casein (CAS) or whey protein isolate (WPI). Full details of the dietary compositions can be found in the paper supplementary table 1. Complete meta-data are in the meta-data tab of the file. Means for each diet derived from these individual values are presented in Figure 1B-D.

本实验旨在分析膳食宏量营养素对体重与能量摄入的影响。研究共设置18种不同膳食，在单一品系雄性C57BL/6小鼠中开展饲喂测试。本文件包含暴露于18种膳食之一、连续饲喂12周的雄性C57BL/6小鼠的个体数据及笼均数据：每周记录每只小鼠的体重（Body Weight, BW）与每笼的能量摄入（Energy Intake, EI），并在实验结束时计算最终体重增重。每种膳食对应11~12只实验动物。膳食处理方案由3个脂肪水平（按能量占比分别为20%、40%、55%）与3个蛋白质水平（按能量占比分别为10%、20%、30%）组合而成，蛋白质来源为酪蛋白（Casein, CAS）或分离乳清蛋白（Whey Protein Isolate, WPI）。膳食组成的完整细节可查阅论文补充表1。完整元数据（Meta-data）存储于该文件的元数据标签页中。基于上述个体数值计算得到的各膳食均值结果展示于图1B-D中。