Effectiveness of CA 15-3 and FDG-PET/CT in detecting recurrent breast cancer in patients with suspected recurrence and in asymptomatic patients.

FN, false negative; FP, false positive; PPV, positive predictive value, NPV, negative predictive value, TN, true negative; TP, true positive; Group 1, patients with elevated serum CA 15-3 levels>31.3 U/ml; Group 2, patients with clinical/radiologic suspicions of recurrences without serum CA 15-3 level increases;*, P†, P = 0.04 FDG-PET/CT vs. serum CA 15-3;§, P = 0.013 suspected recurrence vs. asymptomatic;∣, P = 0.012 Group 1 vs. asymptomatic.Effectiveness of CA 15-3 and FDG-PET/CT in detecting recurrent breast cancer in patients with suspected recurrence and in asymptomatic patients.