Enantioselective Metal-Free Hydrogenations of Disubstituted Quinolines
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https://figshare.com/articles/dataset/Enantioselective_Metal_Free_Hydrogenations_of_Disubstituted_Quinolines/2097853
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资源简介:
A metal-free
hydrogenation of 2,4-disubstituted quinolines was
realized for the first time using chiral diene derived borane catalysts
to furnish the corresponding tetrahydroquinolines in 75–98%
yields with 95/5−99/1 dr’s and 86–98% ee’s.
This catalytic system was also effective for 2,3-disubstituted quinolines
to give moderate to good ee’s.
创建时间:
2016-02-12



