Additional file 1: of Unsupervised correction of gene-independent cell responses to CRISPR-Cas9 targeting

Table S1. Project Score cell lines included in the study with annotations and screening description. Table S2. Quantification of copy number-associated bias before and after CRISPRcleanR correction. Table S3. Recall reduction following CRISPRcleanR correction across control gene-sets and cell lines. Table S4. Recall reduction post CRISPRcleanR correction across controls (mean-variance modeling). Table S5. Cancer driver gene dependencies following CRISPRcleanR correction. Table S6. List of gene signatures downloaded from MSigDB and used as positive controls. (ZIP 6330 kb)

补充表S1：本研究纳入的Project Score细胞系及其注释信息与筛选说明
补充表S2：CRISPRcleanR校正前后与拷贝数相关的偏倚量化结果
补充表S3：在对照基因集与细胞系范围内的CRISPRcleanR校正后召回率降低情况
补充表S4：采用均值-方差建模的对照分组中CRISPRcleanR校正后的召回率降低情况
补充表S5：CRISPRcleanR校正后的癌症驱动基因依赖情况
补充表S6：从分子特征数据库（MSigDB）下载并用作阳性对照的基因特征列表（压缩包大小：6330 KB）