The transforming growth factor β (TGFβ) superfamily proteins are principle regulators of numerous biological functions. Although recent studies have gained tremendous insights into this growth factor
We have found several genetic changes in the TGF-beta-type II receptor gene in human gastric cancer cell lines resistant to the growth inhibitory effect of TGF-beta. Southern blot analysis showed dele
0, negative staining (−); 1–4, weak staining (+); 5–8, moderate staining (++); and 9–12, intense staining (+++). The Fisher exact test was used for intergroup comparisons of immunohistochemistry score
