Evaluation of metabolic network reduction and comparability to genome-scale metabolic networks.

Genome-scale and reduced-scale metabolic networks were compared using flux variability analysis whilst exposed to different environmental conditions. A percentage of the maximum uptake rate (20%, 60% and 100%) for each nutrient was cross-combined with all other nutrient levels in order to generate 81 conditions in the case of four nutrients and 27 conditions in the case of three nutrients. Presented is the median percentage of all reactions having a minimal flux or maximum flux difference falling within the respective category (with standard deviation in brackets).