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An axonal guidance cue Semaphorin 6D orchestrates systemic metabolism and myelopoiesis through tuning sympathetic innervation

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The goal of this study is to characterize the molecular basis for enhanced myelopoiesis in Sema6d-/- mice fed a high fat diet. WT and Sema6d-/- mice were fed with either control or high fat diet for 3 months. Hematopoietic stem cells and multipotent progenitors were sorted from the bone marrow.

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