Magnetoencephalography (MEG) recordings from a phantom with Deep Brain Stimulation (DBS) artefacts

This dataset was acquired in an experiment aimed at testing the effects of Deep Brain Stimulation (DBS) artefacts on MEG recordings using MEG phantom. The experimental procedures are described and the results are reported in the following publication: Oswal A, Jha A, Neal S, Reid A, Bradbury D, Aston P, Limousin P, Foltynie T, Zrinzo L, Brown P, Litvak V. Analysis of simultaneous MEG and intracranial LFP recordings during Deep Brain Stimulation: a protocol and experimental validation. J Neurosci Methods. 2016 Mar 1;261:29-46. doi: 10.1016/j.jneumeth.2015.11.029. Epub 2015 Dec 14. We tested different combinations of presence of ferromagnetic connection wires, movements designed to emulate breathing and heart-beat related artefacts in real patients (see paper for details) and DBS which could be bipolar (only inducing weak artefacts) and monopolar (inducing severe artefacts). We tested 3 stimulation frequencies: 5Hz, 20Hz and 130Hz The datasets included here are as follows: phantom090715_BrainampDBS_20150709_01.ds.zip -wires+ , movement-, stimulation-phantom090715_BrainampDBS_20150709_02.ds.zip - wires- , movement-, stimulation- %This is a clean dataset that can be used as a referencephantom090715_BrainampDBS_20150709_03.ds.zip - wires- , movement-, stimulation+130Hz monopolarphantom090715_BrainampDBS_20150709_04.ds.zip - wires- , movement+, stimulation+130Hz monopolarphantom090715_BrainampDBS_20150709_05.ds.zip - wires- , movement-, stimulation+130Hz monopolarphantom090715_BrainampDBS_20150709_06.ds.zip - wires+ , movement-, stimulation+130Hz monopolarphantom090715_BrainampDBS_20150709_07.ds.zip - wires+ , movement+, stimulation+130Hz monopolar %This is the most realistic dataset for clinical frequency DBSphantom090715_BrainampDBS_20150709_08.ds.zip - wires+ , movement+, stimulation-phantom090715_BrainampDBS_20150709_09.ds.zip - wires+ , movement-, stimulation+20Hz monopolarphantom090715_BrainampDBS_20150709_10.ds.zip - wires+ , movement-, stimulation+5Hz monopolarphantom090715_BrainampDBS_20150709_11.ds.zip - wires+ , movement+, stimulation+5Hz monopolarphantom090715_BrainampDBS_20150709_12.ds.zip - wires+ , movement+, stimulation+20Hz monopolarphantom090715_BrainampDBS_20150709_13.ds.zip - wires+ , movement+, stimulation+130Hz bipolarphantom090715_BrainampDBS_20150709_14.ds.zip - wires+ , movement+, stimulation+20Hz bipolarphantom090715_BrainampDBS_20150709_15.ds.zip - wires+ , movement+, stimulation+5Hz bipolarphantom090715_BrainampDBS_20150709_16.ds.zip - wires- , movement+, stimulation+20Hz monopolarphantom090715_BrainampDBS_20150709_17.ds.zip - wires- , movement+, stimulation+5Hz monopolarphantom090715_BrainampDBS_20150709_18.ds.zip - wires- , movement-, stimulation+5Hz monopolarphantom090715_BrainampDBS_20150709_19.ds.zip - wires- , movement-, stimulation+20Hz monopolar phantom.mov - movie showing the phantom movementreadme.txt - this file The MEG datasets also have accompanying BrainVision data sets where a copy of the 27 Hz sinusoid waveform fed to the phantom 'brain' source was stored. Since these are not required for testing artefact removal methods and using them would require merging with MEG we do not share them here but they could be provided on request. This work was supported by the Medical Research Council and the National Institute for Health Research University College London Hospitals Biomedical Research Centre.The UK MEG community is supported by Medical Research Council grant MR/K005464/1. The Wellcome Trust Centre for Neuroimaging is supported by core funding from the Wellcome Trust 091593/Z/10/Z. Please contact Vladimir Litvak [e-mail] for any additional information本数据集源自一项实验，旨在通过脑磁图（MEG）体模测试脑深部刺激（DBS）伪影对脑磁图记录的影响。相关实验流程与研究结果已发表于下述论文：Oswal A、Jha A、Neal S、Reid A、Bradbury D、Aston P、Limousin P、Foltynie T、Zrinzo L、Brown P、Litvak V. 《脑深部刺激期间同步脑磁图与颅内局部场电位（intracranial LFP）记录的分析：方案与实验验证》，《神经科学方法学杂志》，2016年3月1日，261卷：29-46页。DOI: 10.1016/j.jneumeth.2015.11.029，2015年12月14日在线发表。 本实验测试了多种组合条件，包括铁磁连接导线的有无、模拟真实患者呼吸与心跳相关伪影的运动状态，以及两种类型的脑深部刺激：双极刺激（仅引发轻微伪影）与单极刺激（引发严重伪影）。本次测试涵盖3种刺激频率：5Hz、20Hz与130Hz。 本批次包含的数据集详情如下： 1. phantom090715_BrainampDBS_20150709_01.ds.zip：含铁磁导线、无运动模拟、无刺激 2. phantom090715_BrainampDBS_20150709_02.ds.zip：无铁磁导线、无运动模拟、无刺激 【注】本数据集为干净参考数据集，可作为对照使用 3. phantom090715_BrainampDBS_20150709_03.ds.zip：无铁磁导线、无运动模拟、130Hz单极刺激 4. phantom090715_BrainampDBS_20150709_04.ds.zip：无铁磁导线、有运动模拟、130Hz单极刺激 5. phantom090715_BrainampDBS_20150709_05.ds.zip：无铁磁导线、无运动模拟、130Hz单极刺激 6. phantom090715_BrainampDBS_20150709_06.ds.zip：含铁磁导线、无运动模拟、130Hz单极刺激 7. phantom090715_BrainampDBS_20150709_07.ds.zip：含铁磁导线、有运动模拟、130Hz单极刺激 【注】本数据集为适配临床刺激频率的最真实体模数据集 8. phantom090715_BrainampDBS_20150709_08.ds.zip：含铁磁导线、有运动模拟、无刺激 9. phantom090715_BrainampDBS_20150709_09.ds.zip：含铁磁导线、无运动模拟、20Hz单极刺激 10. phantom090715_BrainampDBS_20150709_10.ds.zip：含铁磁导线、无运动模拟、5Hz单极刺激 11. phantom090715_BrainampDBS_20150709_11.ds.zip：含铁磁导线、有运动模拟、5Hz单极刺激 12. phantom090715_BrainampDBS_20150709_12.ds.zip：含铁磁导线、有运动模拟、20Hz单极刺激 13. phantom090715_BrainampDBS_20150709_13.ds.zip：含铁磁导线、有运动模拟、130Hz双极刺激 14. phantom090715_BrainampDBS_20150709_14.ds.zip：含铁磁导线、有运动模拟、20Hz双极刺激 15. phantom090715_BrainampDBS_20150709_15.ds.zip：含铁磁导线、有运动模拟、5Hz双极刺激 16. phantom090715_BrainampDBS_20150709_16.ds.zip：无铁磁导线、有运动模拟、20Hz单极刺激 17. phantom090715_BrainampDBS_20150709_17.ds.zip：无铁磁导线、有运动模拟、5Hz单极刺激 18. phantom090715_BrainampDBS_20150709_18.ds.zip：无铁磁导线、无运动模拟、5Hz单极刺激 19. phantom090715_BrainampDBS_20150709_19.ds.zip：无铁磁导线、无运动模拟、20Hz单极刺激 20. phantom.mov：展示体模运动的视频文件 21. readme.txt：本说明文件 本次提供的脑磁图数据集附带BrainVision数据集（BrainVision），其中存储了输入至体模「脑」信号源的27Hz正弦波形副本。由于此类数据无需用于伪影去除方法的测试，且需与脑磁图数据合并后方可使用，因此本次未共享该类数据，但可根据申请提供。 本研究得到了医学研究理事会与国家健康与护理研究所伦敦大学学院医院生物医学研究中心的资助。英国脑磁图社区得到了医学研究理事会项目MR/K005464/1的支持。惠康信托神经成像中心得到了惠康信托基金091593/Z/10/Z的核心资助。如需获取更多信息，请联系弗拉基米尔·利特瓦克（Vladimir Litvak），邮箱：[e-mail]。