Comparison between gene set enrichment validation results for ZFP36-inferred target genes obtained using different metrics of statistical-dependency.
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Abbreviations: KO, Tis11/ZFP36 knock-out mouse fibroblasts; NES, normalised enrichment score from Kolmogorov-Smirnov gene set enrichment analysis; FDR, false discovery rate q value from Kolmogorov-Smirnov gene set enrichment analysis; MIC, maximum information coefficient; MI, mutual information, LR, linear regression coefficient.aGene set representing 237 mRNAs displaying significant up-regulation in expression in fibroblasts from Tis11/ZFP36-deficient mouse fibroblasts [21].bGene set representing 152 mRNAs displaying significantly decreased rate of degradation in Tis11/ZFP36-deficient mouse fibroblasts [22].
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2015-12-02
