Bacteriophage anti-defense genes that neutralize TIR and STING immune responses
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Bacteriophage antidefense genes that neutralize TIR and STING immune responses
Programmed cell suicide of infected bacteria, known as abortive infection (Abi), serves as a central immune defense strategy to prevent the spread of bacteriophage viruses and other invasive genetic e
NIAID Data Ecosystem30
Evasion of antiviral bacterial immunity by phage tRNAs
Retrons are bacterial genetic elements that encode a reverse transcriptase and, in combination with toxic effector proteins, can serve as antiphage defense systems. However, the mechanisms of action o
NIAID Data Ecosystem10
Viruses encode tRNA and anti-retron to evade bacterial immunity
Retrons are bacterial genetic retroelements that encode reverse transcriptase capable of producing multicopy single-stranded DNA (msDNA) and function as antiphage defense systems. Phages employ severa
NIAID Data Ecosystem00
Viruses encode tRNA and anti-retron to evade bacterial immunity
Retrons are bacterial genetic retroelements that encode reverse transcriptase capable of producing multicopy single-stranded DNA (msDNA) and function as antiphage defense systems. Phages employ severa
NIAID Data Ecosystem10
Phage homing endonuclease facilitates evasion of the antiphage defenses through segmental amplification of anti-defense factors
Bacteriophages deploy diverse genetic strategies to overcome bacterial immunity, yet the mechanisms that enable immune escape remain incompletely understood. Here, we show that the phage homing endonu
NIAID Data Ecosystem00
