Bacteriophage anti-defense genes that neutralize TIR and STING immune responses
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Bacteriophage antidefense genes that neutralize TIR and STING immune responses
Programmed cell suicide of infected bacteria, known as abortive infection (Abi), serves as a central immune defense strategy to prevent the spread of bacteriophage viruses and other invasive genetic e
NIAID Data Ecosystem40
Viruses encode tRNA and anti-retron to evade bacterial immunity
Retrons are bacterial genetic retroelements that encode reverse transcriptase capable of producing multicopy single-stranded DNA (msDNA) and function as antiphage defense systems. Phages employ severa
NIAID Data Ecosystem10
Viruses encode tRNA and anti-retron to evade bacterial immunity [Ec83]
Retrons are bacterial genetic retroelements that encode reverse transcriptase capable of producing multicopy single-stranded DNA (msDNA) and function as antiphage defense systems. Phages employ severa
NIAID Data Ecosystem10
Phase Variable O Antigen Biosynthetic Genes Control Expression of the Major Protective Antigen and Bacteriophage Receptor in Vibrio cholerae O1
The Vibrio cholerae lipopolysaccharide O1 antigen is a major target of bacteriophages and the human immune system and is of critical importance for vaccine design. We used an O1-specific lytic bacteri
NIAID Data Ecosystem20
Evasion of antiviral bacterial immunity by phage tRNAs
Retrons are bacterial genetic elements that encode a reverse transcriptase and, in combination with toxic effector proteins, can serve as antiphage defense systems. However, the mechanisms of action o
NIAID Data Ecosystem10
