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Investigation of the role of CYLD tumor suppressor in splenic marginal zone lymphoma development

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/ERP160117
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资源简介:
CYLD tumor suppressor was ablated, using CRISPR/Cas9 system, in SL-15 cell line, which was established from a patient with splenic marginal zone lymphoma (SMZL), in the chronic phase of the disease. CYLD KO and control monoclonal populations were established and our findings uncover a novel role of CYLD as a key regulator in SMZL pathogenesis, dissemination and resistance to targeted agents.
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2025-01-16
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