Transcriptome analysis after knockdown of target genes (either HSP27 or TGF-β1, both HSP27 and TGF-β1) via shRNAs in MDA-MB-231 cells. Transcriptome analysis after knockdown of target genes (either HSP27 or TGF-β1, both HSP27 and TGF-β1) via shRNAs in MDA-MB-231 cells

Comparing expression profiles : among comparable samples in which target genes are knocked down Global gene expression profiling has shown that more than 1500 (3.2%) genes over 2-fold gene fluctuations are differentially expressed in shTGF-β1-treated cells compared to control shRNA-treated cells. Overall design: Analysis of differentially expressed genes in a total of 4 samples, a total of 3 comparative combinations.