Percentage of paracetamol recovery, leftover and loss for one 500 mg paracetamol tablet crushed in each of 24 crushing devices (n = 3) followed by tapping the powder out.

A significant difference in paracetamol recovery for each crusher compared with the control (whole tablet, n = 10) is indicated (* p < 0.05, ** p<0.01, *** p<0.001,—no difference). See Supplementary information for details and images of each crusher and disposable vessel.