X-ray crystal structure of human mitochondrial branched chain aminotransferase (BCATm) complexed with gabapentin

X-ray crystal structure of human mitochondrial branched chain aminotransferase (BCATm) complexed with gabapentin Descriptor: ACETIC ACID, PYRIDOXAL-5'-PHOSPHATE, [1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID, ... Authors: Goto, M, Miyahara, I, Hirotsu, K, Conway, M, Yennawar, N, Islam, M.M, Hutson, S.M. Deposit date: 2005-06-20 Release date: 2005-09-06 Last modified: 2025-03-26 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. J.Biol.Chem., 280, 2005人类线粒体支链氨基酸转氨酶（BCATm）与加巴喷丁结合的X射线晶体结构。描述符：乙酸、吡哆醛-5'-磷酸、[1-(氨甲基)环己基]乙酸，……。作者：Goto M、Miyahara I、Hirotsu K、Conway M、Yennawar N、Islam MM、Hutson SM。沉积日期：2005-06-20，发布日期：2005-09-06，最后修改日期：2025-03-26。实验方法：X射线衍射（分辨率1.8埃）。引用文献：抗惊厥药物加巴喷丁对支链氨基酸转氨酶同工酶特异性抑制的结构决定因素。《生物化学杂志》，280卷，2005年。