Staphylococcus aureus Dihydropteroate Synthase (saDHPS) F17L E208K double mutant structure
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Staphylococcus aureus Dihydropteroate Synthase (saDHPS) F17L E208K double mutant structure Descriptor: 4-{[(2-amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzene-1-sulfonamide, Dihydropteroate synthase Authors: Gajewski, S, Griffith, E.C, Wu, Y, White, S.W. Deposit date: 2018-03-02 Release date: 2018-08-22 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations inStaphylococcus aureusDihydropteroate Synthase. Front Microbiol, 9, 2018
金黄色葡萄球菌二氢蝶酸合酶(Staphylococcus aureus Dihydropteroate Synthase, saDHPS)F17L E208K双突变体结构
配体描述:4-{[(2-氨基-4-氧代-3,4-二氢蝶啶-6-基)甲基]氨基}-N-(3,4-二甲基-1,2-恶唑-5-基)苯-1-磺酰胺,二氢蝶酸合酶(Dihydropteroate Synthase)
作者:Gajewski, S、Griffith, E.C、Wu, Y、White, S.W.
提交日期:2018-03-02
发布日期:2018-08-22
最后修改日期:2024-03-13
实验方法:X射线衍射(X-RAY DIFFRACTION,分辨率2.3埃)
引用文献:《金黄色葡萄球菌二氢蝶酸合酶反复出现的磺胺类药物耐药突变的结构与功能基础》,《微生物学前沿(Front Microbiol)》,2018年,第9卷
创建时间:
2018-03-02



