Upper limbs fitts' task - global exercise versus focused handwriting exercise training in Parkinson’s disease

Considering PwPD rehabilitation, some interventions prioritise global training such as aerobic exercise, aquatic therapy, dance, strength/resistance, balance training, and endurance training, while others focus on upper limb specific training such as hand exercises, and writing activities. In our previous studies we found improvement in motor symptoms in favour of the exercise group and improvements in writing amplitude in favour of the handwriting group. However, there is still a gap in the knowledge: “What is the influence of global and specific movements in the improvement in accuracy and speed?”. The answer for this question would help clinicians to understand how to promote better clinical treatments in order to improve the accuracy and speed of PwPD, improving their functional movements.
Seventy PwPD, right-side dominant were randomised 1:1 into two six-month training protocol groups; 35 PwPD performed global exercise training and 35 specific training (handwriting upper limb exercise movements). Assessments of speed-accuracy and trade-off were carried out at baseline, at 3 and 6 months of training, and at a 12-month follow-up.

针对帕金森病患者（People with Parkinson's Disease, PwPD）的康复训练，部分干预方案优先采用整体性训练，例如有氧运动、水疗、舞蹈、力量/抗阻训练、平衡训练与耐力训练，而其余方案则聚焦于上肢针对性训练，例如手部练习与书写活动。在既往研究中，我们发现运动训练组的运动症状得到改善，而书写训练组的书写幅度获得提升。然而目前仍存在认知空白：“整体性与针对性运动对动作准确性与速度的提升有何影响？”该问题的解答将帮助临床医师明确如何优化临床治疗方案，以改善帕金森病患者的动作准确性与速度，进而提升其功能性运动能力。
本研究纳入70名右利手帕金森病患者，以1:1的比例随机分配至两个为期6个月的训练方案组：其中35名接受整体性运动训练，另外35名接受针对性训练（上肢书写运动训练）。研究分别在基线、训练第3个月、第6个月以及12个月随访节点，对动作速度-准确性及其权衡效应进行评估。