E. coli dihydroorotate dehydrogenase bound to the inhibitor HMNQ

E. coli dihydroorotate dehydrogenase bound to the inhibitor HMNQ Descriptor: 3-methyl-2-[(2E)-non-2-en-1-yl]quinolin-4(1H)-one, Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, ... Authors: Horwitz, S.M, Ambarian, J.A, Davis, K.M. Deposit date: 2021-12-13 Release date: 2022-03-02 Last modified: 2024-12-25 Method: X-RAY DIFFRACTION (2.62 Å) Cite: Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines. Rsc Chem Biol, 3, 2022结合抑制剂HMNQ的大肠杆菌（E. coli）二氢乳清酸脱氢酶（Dihydroorotate dehydrogenase） 组分描述：3-甲基-2-[(2E)-2-壬烯-1-基]喹啉-4(1H)-酮、醌类二氢乳清酸脱氢酶（Dihydroorotate dehydrogenase (quinone)）、黄素单核苷酸（FLAVIN MONONUCLEOTIDE）等 作者：Horwitz, S.M、Ambarian, J.A、Davis, K.M. 存档日期：2021-12-13 发布日期：2022-03-02 最后修改日期：2024-12-25 实验方法：X射线衍射法（X-RAY DIFFRACTION），分辨率2.62埃（Å） 引用文献：《细菌羟烷基喹啉类化合物对药物靶点二氢乳清酸脱氢酶的抑制作用结构解析》（Structural insights into inhibition of the drug target dihydroorotate dehydrogenase by bacterial hydroxyalkylquinolines），发表于《RSC化学生物学》（Rsc Chem Biol）第3卷，2022年