Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 5-diphosphoinositol 1,3,4,6-tetrakisphosphate (5-PP-IP4), Mg, and Fluoride ion
收藏Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP1/NUDT3) in complex with 5-diphosphoinositol 1,3,4,6-tetrakisphosphate (5-PP-IP4), Mg, and Fluoride ion Descriptor: (1r,2R,3S,4r,5R,6S)-4-hydroxy-2,3,5,6-tetrakis(phosphonooxy)cyclohexyl trihydrogen diphosphate, CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, ... Authors: Zong, G.N, Wang, H.C, Shears, S.B. Deposit date: 2020-04-24 Release date: 2021-03-03 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: New structural insights reveal an expanded reaction cycle for inositol pyrophosphate hydrolysis by human DIPP1. Faseb J., 35, 2021
二磷酸肌醇多磷酸磷酸水解酶1(Diphosphoinositol polyphosphate phosphohydrolase 1,DIPP1/NUDT3)与5-二磷酸肌醇1,3,4,6-四磷酸(5-diphosphoinositol 1,3,4,6-tetrakisphosphate,5-PP-IP4)、镁离子(Mg)及氟离子形成的复合物。
描述符:(1r,2R,3S,4r,5R,6S)-4-羟基-2,3,5,6-四(膦酰氧基)环己基三氢二磷酸、氯离子、二磷酸肌醇多磷酸磷酸水解酶1……
作者:宗,G.N.、王,H.C.、希尔斯,S.B.
提交日期:2020-04-24
发布日期:2021-03-03
最后修改日期:2024-03-06
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.7埃(Å)
引用文献:新的结构见解揭示了人类DIPP1水解肌醇焦磷酸的扩展反应循环。《Faseb J.》,第35卷,2021年
创建时间:
2020-04-24



